abstract：PURPOSE:To report the 24-month anatomic and Early Treatment Diabetic Retinopathy Study (ETDRS) best-corrected visual acuity (BCVA) response after primary intravitreal bevacizumab (Avastin; Genentech, Inc., San Francisco, CA; 1.25 or 2.5 mg) in patients with diffuse diabetic macular edema (DDME). In addition, a comparis...

journal_title：Ophthalmology

authors： Arevalo JF,Sanchez JG,Wu L,Maia M,Alezzandrini AA,Brito M,Bonafonte S,Lujan S,Diaz-Llopis M,Restrepo N,Rodríguez FJ,Udaondo-Mirete P,Pan-American Collaborative Retina Study Group.

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:To evaluate safety and efficacy of an intracorneal inlay for the correction of hyperopia. DESIGN:A prospective, nonrandomized, noncomparative, 2-center study. PARTICIPANTS:Thirty-four hyperopic eyes were implanted with a hydrogel intracorneal inlay (Permavision, Anamed, Lake Forest, CA). Preoperative hyperopi...

journal_title：Ophthalmology

authors： Mulet ME,Alio JL,Knorz MC

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the intraocular pressure (IOP) reduction achieved by the most frequently prescribed antiglaucoma drugs in patients with normal tension glaucoma (NTG). DESIGN:Systematic review and meta-analysis. PARTICIPANTS:Fifteen randomized clinical trials reported 25 arms for peak IOP reduction, 16 arms for ...

journal_title：Ophthalmology

authors： Cheng JW,Cai JP,Wei RL

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To examine the microscopic anatomic features of lower eyelid retractors in Caucasians, specifically looking for an anatomic division of the retractors into 2 layers, as is present in the Asian eyelid. DESIGN:Experimental anatomic study. PARTICIPANTS:Seven Caucasian cadavers (13 lower eyelids: 7 right and 6 le...

journal_title：Ophthalmology

authors： Kakizaki H,Chan W,Madge SN,Malhotra R,Selva D

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To determine the incidence of full-thickness macular holes in Olmsted County, Minnesota. DESIGN:Population-based retrospective chart review (cross-sectional study). PARTICIPANTS:Ninety-four eyes of 85 patients who were residents of Olmsted County, Minnesota. METHODS:A population-based retrospective chart rev...

journal_title：Ophthalmology

authors： McCannel CA,Ensminger JL,Diehl NN,Hodge DN

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To learn whether dilating the pupil will have an impact on glare testing for cataract evaluation. DESIGN:Evaluation of diagnostic test. PARTICIPANTS:Fifty-four adult patients at the Jones Eye Institute at the University of Arkansas for Medical Sciences. METHODS:One eye of each patient was randomized for stud...

journal_title：Ophthalmology

authors： Wiggins MN,Irak-Dersu I,Turner SD,Thostenson JD

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To investigate the ability of sectorial analysis using the Heidelberg Retinal Tomograph 3 (HRT3) to discriminate between healthy and glaucomatous eyes and to determine whether this is affected by disc size and glaucoma severity. DESIGN:Multicenter, cross-sectional evaluation of diagnostic tests. PARTICIPANTS:...

journal_title：Ophthalmology

authors： Oddone F,Centofanti M,Iester M,Rossetti L,Fogagnolo P,Michelessi M,Capris E,Manni G

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To identify any mutation of the UbiA prenyltransferase domain-containing protein 1 (UBIAD1) gene in Japanese patients with Schnyder's crystalline corneal dystrophy (SCCD) and to investigate in vivo microstructural phenotype and genotype correlations using laser scanning confocal microscopy (Heidelberg Retina ...

journal_title：Ophthalmology

authors： Kobayashi A,Fujiki K,Murakami A,Sugiyama K

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:To analyze hyperreflective foci typically seen in diabetic macular edema (DME) in optical coherence tomography (OCT). DESIGN:Prospective clinical trial. PARTICIPANTS:Twelve consecutive patients with treatment-naïve, clinically significant DME. METHODS:During a same-day examination, a standardized visual acui...

journal_title：Ophthalmology

authors： Bolz M,Schmidt-Erfurth U,Deak G,Mylonas G,Kriechbaum K,Scholda C,Diabetic Retinopathy Research Group Vienna.

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To estimate the incremental cost-effectiveness of routine glaucoma assessment and treatment under current eye care visit and treatment patterns and different levels of treatment effectiveness (from randomized trials). DESIGN:We compared the costs and benefits of routine glaucoma assessment and treatment comp...

journal_title：Ophthalmology

authors： Rein DB,Wittenborn JS,Lee PP,Wirth KE,Sorensen SW,Hoerger TJ,Saaddine JB

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety, efficacy, predictability, stability, and complications of the foldable Artiflex iris-fixated intraocular lens (Ophtec BV, Groningen, The Netherlands) for the correction of myopia in phakic eyes. DESIGN:Prospective, nonrandomized, open-label, multicenter trial. PARTICIPANTS:Two hundre...

journal_title：Ophthalmology

authors： Dick HB,Budo C,Malecaze F,Güell JL,Marinho AA,Nuijts RM,Luyten GP,Menezo JL,Kohnen T

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:To report the immediate postoperative complications and the 6- and 12-month clinical results in a large series of cases undergoing the new triple-procedure Descemet's stripping automated endothelial keratoplasty (DSAEK) and concurrent cataract surgery. DESIGN:Prospective, noncomparative, interventional case se...

journal_title：Ophthalmology

authors： Terry MA,Shamie N,Chen ES,Phillips PM,Shah AK,Hoar KL,Friend DJ

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:To report the usefulness of the Boston type I keratoprosthesis (Massachusetts Eye and Ear Infirmary, Boston, MA) in the management of corneal opacification, corneal limbal stem cell failure, or both in a large single-surgeon series. DESIGN:Retrospective review of consecutive clinical case series. PARTICIPANTS...

journal_title：Ophthalmology

authors： Aldave AJ,Kamal KM,Vo RC,Yu F

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:To assess the ability of the new pattern electroretinogram optimized for glaucoma detection (PERGLA) paradigm to discriminate between healthy individuals and individuals with glaucomatous optic neuropathy (GON). DESIGN:Cross-sectional study. PARTICIPANTS:One hundred forty-two eyes of 71 participants (42 healt...

journal_title：Ophthalmology

authors： Bowd C,Vizzeri G,Tafreshi A,Zangwill LM,Sample PA,Weinreb RN

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To assess visual acuity (VA) and 2 questionnaires of health-related quality of life--the Visual Function 14 (VF-14) index and the Medical Outcomes Study Short Form 36 Health Survey (SF-36)--as instruments for capturing clinically important changes after cataract surgery. DESIGN:Prospective, observational stu...

journal_title：Ophthalmology

authors： Bilbao A,Quintana JM,Escobar A,García S,Andradas E,Baré M,Elizalde B,IRYSS-Cataract Group.

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:To determine the incidence of retinopathy of prematurity (ROP) over a 2-year period before and after a change in the practice of oxygen supplementation. DESIGN:Nonrandomized, retrospective study. PARTICIPANTS:All infants in a single Level III neonatal intensive care unit between the years of 2005 and 2007. M...

journal_title：Ophthalmology

authors： Sears JE,Pietz J,Sonnie C,Dolcini D,Hoppe G

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To compare the long-term efficacy of intraoperative 5-fluorouracil (5-FU) and mitomycin C (MMC) in primary trabeculectomy. DESIGN:Comparative case series and extension of a prospective, randomized controlled trial. PARTICIPANTS:One hundred fifteen eyes of 103 subjects undergoing primary trabeculectomy with ...

journal_title：Ophthalmology

authors： Palanca-Capistrano AM,Hall J,Cantor LB,Morgan L,Hoop J,WuDunn D

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:To establish the thresholds for "real change" in stereoacuity by defining long-term test-retest variability as 95% limits of agreement for 4 stereoacuity tests. DESIGN:Retrospective cohort study. PARTICIPANTS AND CONTROLS:We identified 36 patients (median, 17 years; range, 7-76) with any type of stable strabi...

journal_title：Ophthalmology

authors： Adams WE,Leske DA,Hatt SR,Holmes JM

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:To assess the risk of advanced age-related macular degeneration (AMD) developing after cataract surgery. DESIGN:Cohort study. PARTICIPANTS:Four thousand five hundred seventy-seven participants (8050 eyes) from a multicenter, controlled, randomized clinical trial, the Age-Related Eye Disease Study (AREDS). ME...

journal_title：Ophthalmology

authors： Chew EY,Sperduto RD,Milton RC,Clemons TE,Gensler GR,Bressler SB,Klein R,Klein BE,Ferris FL 3rd

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:To evaluate the outcomes of combined deep sclerectomy and trabeculectomy (penetrating deep sclerectomy) in pediatric glaucoma. DESIGN:Retrospective, nonconsecutive, noncomparative, interventional case series. PARTICIPANTS:Children suffering from pediatric glaucoma who underwent surgery between March 1997 and ...

journal_title：Ophthalmology

authors： Feusier M,Roy S,Mermoud A

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether interleukin (IL)-6 or vascular endothelial growth factor (VEGF) influences macular edema in patients with central retinal vein occlusion (CRVO). DESIGN:Retrospective case-control study. PARTICIPANTS:Twenty-seven patients who had macular edema with CRVO and 16 patients with nonischemic...

journal_title：Ophthalmology

authors： Noma H,Funatsu H,Mimura T,Harino S,Hori S

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To evaluate photodynamic therapy (PDT) for symptomatic circumscribed choroidal hemangioma (CCH). DESIGN:Prospective, multicenter, nonrandomized clinical trial. PARTICIPANTS:Thirty-one eyes of 31 patients with posterior pole CCH and symptoms caused by exudation into the macular area. INTERVENTION:Photodynamic...

journal_title：Ophthalmology

authors： Boixadera A,García-Arumí J,Martínez-Castillo V,Encinas JL,Elizalde J,Blanco-Mateos G,Caminal J,Capeans C,Armada F,Navea A,Olea JL

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To investigate refractive error in eyes with nonarteritic anterior ischemic optic neuropathy (NA-AION) and its relationship to cup/disc (C/D) ratio. DESIGN:Cohort study. PARTICIPANTS:A total of 608 consecutive patients with NA-AION. METHODS:At first visit, all patients had a comprehensive ophthalmic evalua...

journal_title：Ophthalmology

authors： Hayreh SS,Zimmerman MB

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:To evaluate the clinical features and management of diffuse infiltrating retinoblastoma. DESIGN:Retrospective case series. PARTICIPANTS:Thirty-four eyes in 32 patients. METHODS:The patients' records were reviewed for patient and tumor features, ocular management, histopathologic findings, and patient surviva...

journal_title：Ophthalmology

authors： Shields CL,Ghassemi F,Tuncer S,Thangappan A,Shields JA

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:To study the associations between long-term and short-term use of topical beta-blockers and mortality. DESIGN:Prospective population-based cohort study. PARTICIPANTS:To examine long-term effects, 3842 participants aged 55 years and older were recruited. To examine short-term effects, 484 incident beta-blocker...

journal_title：Ophthalmology

authors： Müskens RP,Wolfs RC,Witteman JC,Hofman A,de Jong PT,Stricker BH,Jansonius NM

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:To compare efficacies of 1-day, 1-hour, and combined 1-day/1-hour preoperative topical gatifloxacin in eliminating conjunctival bacterial flora. DESIGN:Prospective, comparative case series. PARTICIPANTS:Sixty patients (120 eyes) scheduled to undergo anterior segment intraocular surgery at Stanford University ...

journal_title：Ophthalmology

authors： Moss JM,Nguyen D,Liu YI,Singh K,Montague A,Egbert PR,Kaspar HM,Ta CN

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:To study the 3-year effect of oral nilvadipine, a calcium antagonist, on visual field performance and ocular circulation in open-angle glaucoma (OAG) with low-normal intraocular pressure (IOP). DESIGN:A randomized, placebo-controlled, double-masked, single-center trial. PARTICIPANTS:Patients with OAG who were...

journal_title：Ophthalmology

authors： Koseki N,Araie M,Tomidokoro A,Nagahara M,Hasegawa T,Tamaki Y,Yamamoto S

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To investigate the long-term surgical outcome of Brown syndrome using an intraoperative adjustable superior oblique (SO) tendon suture spacer. DESIGN:Retrospective case series. PARTICIPANTS:Thirteen patients with congenital unilateral Brown syndrome operated on at the Wolfe Eye Clinic from 2001 through 2007...

journal_title：Ophthalmology

authors： Suh DW,Oystreck DT,Hunter DG

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To assess the relative risks (RR) of microbial keratitis (MK) for contemporary contact lens (CL) types and wearing schedules. DESIGN:A 2-year prospective case-control study begun in December 2003. PARTICIPANTS:Cases were 367 CL wearers attending Moorfields Eye Hospital with proven or presumed MK. Controls w...

journal_title：Ophthalmology

authors： Dart JK,Radford CF,Minassian D,Verma S,Stapleton F

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:The purpose of this study was to characterize the contemporary clinical presentation and treatment results of patients with dislocated intraocular lenses (IOLs). DESIGN:Retrospective, noncomparative, single-surgeon interventional case series. PARTICIPANTS:Two hundred eighty-four eyes of 277 patients operated ...

journal_title：Ophthalmology

authors： Kim SS,Smiddy WE,Feuer W,Shi W

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To report the fungal isolates, treatment strategies, and clinical outcomes for a large series of patients with exogenous fungal endophthalmitis. DESIGN:Retrospective, single institution, consecutive case series. PARTICIPANTS:All patients treated at Bascom Palmer Eye Institute between January 1, 1990, and Ju...

journal_title：Ophthalmology

authors： Wykoff CC,Flynn HW Jr,Miller D,Scott IU,Alfonso EC

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:To identity anatomic risk factors involved in the onset of retinal complications causing decrease of visual acuity (VA) in the fellow eyes of highly myopic patients operated for retinal detachment with macular hole (RDMH). DESIGN:Cohort study. PARTICIPANTS:Ninety-eight patients (mean age, 51.5+/-8.0 years) wi...

journal_title：Ophthalmology

authors： Ripandelli G,Coppé AM,Parisi V,Stirpe M

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:To compare the timing, radiologic, and clinical indications for surgical management of orbital floor fractures in the pediatric and adult populations. DESIGN:Retrospective observational case series. PARTICIPANTS:Twenty-four pediatric and 31 adult patients who underwent primary repair of an orbital floor fract...

journal_title：Ophthalmology

authors： Parbhu KC,Galler KE,Li C,Mawn LA

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To describe the prevalence and risk factors for age-related macular degeneration (AMD) in a Japanese population and to compare these with data from a white population. DESIGN:Population-based cross-sectional epidemiologic study. PARTICIPANTS:A population-based sample of Japanese persons 35 years or older fr...

journal_title：Ophthalmology

authors： Kawasaki R,Wang JJ,Ji GJ,Taylor B,Oizumi T,Daimon M,Kato T,Kawata S,Kayama T,Tano Y,Mitchell P,Yamashita H,Wong TY

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To report clinical findings of rare retrobulbar optic nerve hemangioblastomas associated with von Hippel-Lindau disease (VHL). DESIGN:Retrospective observational case series. PARTICIPANTS:Nine patients with VHL. METHODS:The clinical course and magnetic resonance imaging findings of patients with VHL and he...

journal_title：Ophthalmology

authors： Meyerle CB,Dahr SS,Wetjen NM,Jirawuthiworavong GV,Butman JA,Lonser RR,Oldfield E,Rodriguez-Coleman H,Wong WT,Chew EY

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To describe the successful treatment and long-term outcomes of primary ocular surface squamous neoplasia (OSSN) with topical interferon alfa-2b or surgical excision. DESIGN:Retrospective, comparative, interventional case series. PARTICIPANTS:Twenty-nine consecutive patients with OSSN never before treated. ...

journal_title：Ophthalmology

authors： Sturges A,Butt AL,Lai JE,Chodosh J

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To examine the decrease in the intraocular concentration of intravitreally injected triamcinolone acetonide over an 8-month period in a rabbit model. DESIGN:Experimental study. PARTICIPANTS:The study included 18 white New Zealand rabbits. METHODS:The animals received an intravitreal injection of 6 mg triamci...

journal_title：Ophthalmology

authors： Kamppeter BA,Cej A,Jonas JB

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To assess the long-term success rate and to determine factors that predict survival after 5-fluorouracil-augmented needling revision of poorly functioning trabeculectomy blebs. DESIGN:Prospective observational cohort study. PARTICIPANTS:Eighty-one consecutive patients undergoing bleb needling. METHODS:Surviv...

journal_title：Ophthalmology

authors： Rotchford AP,King AJ

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To determine whether multiple B-scan averaging improves the quality of spectral-domain optical coherence tomography (SD OCT) images of the retina. DESIGN:Prospective cross-sectional study. PARTICIPANTS:One hundred one eyes of 84 patients with various retinal diseases. METHODS:A prototype SD OCT system was ...

journal_title：Ophthalmology

authors： Sakamoto A,Hangai M,Yoshimura N

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:To report the frequency and relationship of eyelid retraction, lid lag, lagophthalmos, and von Graefe's sign in a group of patients with Graves' ophthalmopathy and compare these findings to those in a group of normal individuals. DESIGN:Retrospective comparative cohort study. PARTICIPANTS:Fifty consecutive Gr...

journal_title：Ophthalmology

authors： Gaddipati RV,Meyer DR

更新日期：2008-06-01 00:00:00